Publications

  • Publication Reference Year Symeres Authors Customer
    Synthesis of yellow fluorescent dyes derived from benzoxanthene that can be used in colour converters for remote phosphor LED systems Dyes and pigments, 2018, 149, 662-668 2018 Sylvain Hamon, Ton Visser Philips

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  • Publication Reference Year Symeres Authors Customer
    Drug-target residence time: A misleading concept Drug Discovery 23, 1, (2018,) 12-16 2018 Rutger folmer

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    Targeting a Subpocket in Trypanosoma brucei Phosphodiesterase B1 (TbrPDEB1) Enables the Structure-Based Discovery of Selective Inhibitors with Trypanocidal Activity Journal of Medicinal Chemistry, 2018, 61, (9), 3870-3888 2018 Johan Veerman, Toine van de Bergh TI Pharma

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  • Publication Reference Year Symeres Authors Customer
    Microwave-assisted diastereoselective two-step three-component synthesis for rapid access to drug-like libraries of substituted 3-amino-β-lactams Bioorg. Med. Chem. 2018, 26, 41-49 2018 Joyce van den Heuvel, Rik Megens, Jorg Benningshof Leiden University Medical Center

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  • Publication Reference Year Symeres Authors Customer
    Structure–Activity Relationship Studies on (R)-PFI-2 Analogues as Inhibitors of Histone Lysine Methyltransferase SETD7 ChemMedChem, 2018, 13, 1405 – 1413 2018 Eddy Damen, Ruben Leenders, Richard Blaauw Institute for Molecules and Materials

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  • Publication Reference Year Symeres Authors Customer
    Piperidine and octahydropyrano[3,4-c] pyridine scaffolds for drug-like molecular libraries of the European Lead Factory Bioorg. Med. Chem. 2017, 5160 – 5170 2017 Dirk Vandenput, Joeri Scheidt, Jorg Benningshof Leiden Institute of Chemistry

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  • Publication Reference Year Symeres Authors Customer
    Synthesis and Properties of 2-Oxa-6-azaspiro[3.3]heptane Sulfonate Salts Synthesis 2017, 49 (11), 2394-2401 2017 Richard van der Haas, Jeroen Dekker, Eric Damen Bayer Pharma

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  • Publication Reference Year Symeres Authors Customer
    Charting Biologically Relevant Spirocyclic Compound Space Chem. Eur. J. 2017, 23 (3), 703-710 2017 Gerhard Müller, Tim Berkenbosch, Jorg Benningshof ELF

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  • Publication Reference Year Symeres Authors Customer
    Discovery, Structure-Activity Relationship, and Binding Mode of an Imidazo[1,2-a]pyridine Series of Autotaxin Inhibitors J. Med. Chem. 2017, 60 (17), 7371-7392 2017 Jörg Heiermann, Willem Hengelveld, Gregor Pilzak Galapagos

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  • Publication Reference Year Symeres Authors Customer
    Design and Synthesis of Enantiomerically Pure Decahydroquinoxalines as Potent and Selective k-Opioid Receptor Agonists with Anti-Inflammatory Activity in Vivo J. Med. Chem. 2017, 60 (6), 2526-2551 2017 Peter Molenveld, Roy Storcken, Renaud Bouzanne des Mazery, Geert-Jan Sterk, Reshma Autar, Marjon Bolster, Clemens Wagner, Frank van Holst, Anita Wegert Dr. August Wolff

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